Description

Dyclonine Hydrochloride 536-43-6 

Dyclonine Hydrochloride 

536-43-6 
MW: 325.9

MSDS: Avaiable
MF: C18H27NO2 HCl

Sample: Avaiable
Category: API

Min order: 10grams
Quality standard: USP Place of Origin:China
Appearance Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter

throat lozenge.[1] It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt
Applications Pharmaceutical raw materials Used as a local anesthetic.

Dyclonine Hydrochloride 536-43-6 

Function

Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.

Specification